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Combining a fibrate with a statin increases the risk of rhabdomyolysis by more than 10 times the use of a statin alone.
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The FDA has approved a new lipid regulating agentthe ethyl esters of omega-3 fatty acids for the treatment of high triglyceride levels.
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This meta-analysis reviewed trials of antioxidants for prevention of GI cancer.
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Drug-seeking behaviors are commonplace in emergency departments. Many physicians have faced patients with multiple alleged allergies to narcotics who are asking for a medication that the physician never would have initially thought of prescribing, whose medications were stolen, and who become angry, threatening, and agitated upon refusal to refill the stolen prescription. This article defines various terms used in the drug-seeking literature, provides an overview of drug-seeking behaviors, and proposes some techniques to manage these patients both at the individual and at the institutional levels.
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Hypertensive disorders of pregnancy range from chronic pre-existing disease to life-threatening conditions such as HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) and eclampsia. They often represent a continuum from bad to worse. The emergency department physician is likely to evaluate a pregnant patient for many conditions unrelated to the pregnancy itself, and knowledge of abnormalities that warrant further assessment and follow-up is essential.
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Inhaled corticosteroids are the most effective pharmacologic agents in reducing exacerbations in asthmatics.
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The newer, more potent, statin drugs are capable of reducing LDL cholesterol safely and tolerably in most patients thus making a target LDL of 50-70 mg/dL a practical goal, but how low is too low?