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Bendamustine has received FDA approval, after priority review, for the treatment of chronic lymphocytic leukemia.
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A statistically significant improvement in symptoms was observed in the treatment groups, with the honey-child group scoring the best, and the no treatment group doing the most poorly.
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Mild TBI may be associated with brain microhemorrhages and white matter disruption, even with mild or absent symptoms of a postconcussion syndrome.
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The proton pump inhibitor rabeprazole is said to provide rapid acid inhibition, but clinical implications of this have been uncertain. This study shows that a single dose of rabeprazole 20 mg administered 5 hours before therapeutic dosing of aspirin significantly decreases gastroduodenal damage.
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This study from the department of surgery at Washington University School of Medicine in St Louis sought to determine the effect on extubation and reintubation rates of implementing a mandatory daily spontaneous breathing trial (SBT) in every qualifying ventilated patient and reporting its results to the physicians managing that patient.
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Despite the large role that vasopressors play in the management of septic shock, an unfortunately common problem associated with high mortality, few data exist to support using one vasopressor regimen over another.
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Casserly and colleagues administered a case-based questionnaire to physician and nursing staffs at 2 large teaching hospitals in Ireland, to determine their knowledge and experience with respect to a common and potentially deadly event in mechanically ventilated patients with fresh tracheostomies: dislodgement of the tube from the airway during vigorous coughing.
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In This Issue: FDA drug approval to change? Urinary incontinence in women; how metabolism of certain drugs can be predicted by genetic analysis; bowel preps may compromise renal function especially in the elderly according to a new study; FDA Actions.
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This study sought to determine whether the occurrence of in-hospital cardiac arrest at night and on weekends was associated with worse outcomes as compared with arrests during day/evening shifts and on weekdays.
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Regionalized health care systems exist for trauma and neonatal care and efforts are underway to institute similar systems for high-risk surgeries, three fields in which there is a positive relationship between the volume of cases handled and patient outcomes.