Cardiology
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An Update to the Management of Atrial Fibrillation
This focused update to the 2014 guidelines for the management of atrial fibrillation (AF) includes revisions to anticoagulation recommendations and the role of catheter ablation of AF in patients with heart failure.
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Corticosteroid Administration in Sepsis May Be Associated With Lower 28-Day Mortality
In this systematic review and meta-analysis of randomized, controlled trials comparing administration of corticosteroids with placebo or standard supportive care in sepsis, corticosteroids were associated with reduced 28-day mortality.
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Using Ketamine in the Critically Ill: A Clinical Review
This is a guideline for ketamine use in the appropriate clinical setting from the practicing intensivist’s perspective.
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Management of Spontaneous Coronary Artery Dissection
In the largest study to date about patients with spontaneous coronary artery dissection who underwent follow-up angiography, 95% of those who underwent repeat cath more than 30 days later showed spontaneous angiographic healing.
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Impact of Atrial Fibrillation on Survival in Patients With Severe Mitral Regurgitation
A large observational study of patients with severe mitral valve regurgitation due to flail leaflets revealed that atrial fibrillation at entry was associated with excess mortality.
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Who Needs a TEE Prior to Atrial Fibrillation Cardioversion?
A study of patients with atrial fibrillation or flutter undergoing transesophageal echocardiography showed a left atrial appendage thrombus in 8% overall and 4% in those appropriately anticoagulated.
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Medication First? Ablation First? Either Way, Make Weight Loss a Priority
Weight loss management and aggressive risk factor modification associated with slowing or even reversal of atrial fibrillation progression.
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Withdrawal of Medical Therapy Associated With Relapse in Recovered Dilated Cardiomyopathy
In patients with dilated cardiomyopathy and recovered ejection fraction, discontinuation of heart failure medical therapies was associated with a 44% risk of relapse within six months.
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Are the Changes Acute?
Imagine the ECG in the figure was obtained from a previously healthy, middle-aged man who presented to an ambulatory clinic for “indigestion.” How might one interpret the ECG?
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Caplacizumab-yhdp for Injection (Cablivi)
Caplacizumab-yhdp is indicated for the treatment of acquired thrombotic thrombocytopenic purpura in combination with plasma exchange and immunosuppressive therapy.