Cardiology
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Does Physical Activity Lower the Risk of Parkinson’s Disease?
A systematic review and meta-analysis incorporating more than 500,000 subjects revealed that moderate to vigorous physical activity is associated with a significant reduction in development of Parkinson’s disease; this relationship is most pronounced in men.
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Behavioral Interventions in Adults for Weight Loss or Weight Loss Maintenance
The U.S. Preventive Services Task Force evaluated the risks and benefits of interventions for weight loss and weight loss maintenance to prevent complications from obesity and found a moderate net benefit from weight loss-intensive behavioral interventions.
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Can Hypnotherapy Change Our Microbiome?
Gut-directed hypnotherapy provided improvement in irritable bowel syndrome symptoms but failed to cause significant changes in study participants’ microbiome.
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The Effect of Preconception Vitamin D Levels on Live Birth and Pregnancy Loss
This secondary analysis of Effects of Aspirin in Gestation and Reproduction trial found that women with sufficient 25-hydroxyvitamin D levels (≥ 30 ng/mL) were more likely to become pregnant and have a live birth than women with insufficient concentrations of vitamin D.
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An Herbal Steam Bath for Allergies
After four weeks, people with allergic rhinitis in both an herbal steam bath group and a control group showed improvements in some typical rhinitis symptoms.
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PrabotulinumtoxinA-xvfs Injection (Jeuveau)
PrabotulinumtoxinA-xvfs is indicated for temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adults.
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Ripples From Original WHI Study Results Continue: Is This Appropriate?
Recommendations for menopausal hormone therapy were widely publicized and adopted following the original publication of the results of the Women’s Health Initiative, affecting both initiation and continuation of estrogen therapy through at least 2013.
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Dual Antiplatelet Therapy With Cilostazol for Secondary Stroke Prevention (LB3)
In a recent trial, patients treated with dual antiplatelet therapy combining cilostazol with either aspirin or clopidogrel were at a lower risk of ischemic stroke recurrence and at a similar risk of significant bleeding compared to patients treated with aspirin or clopidogrel alone.
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IV to Oral Conversion of Antibiotic Therapy for Bacteremia Due to Enterobacteriaceae
Oral step-down antibiotic therapy (IV to oral conversion) is safe and effective in patients with bloodstream infection due to Enterobacteriaceae.
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Rethinking the Prophylactic Use of Proton Pump Inhibitors in the ICU
The authors of this multicenter, blinded, randomized trial found that among critically ill adults at risk for gastrointestinal (GI) bleeding, fewer patients in the pantoprazole group exhibited clinically important GI bleeding compared to placebo, although mortality at 90 days was similar in both groups.