Cardiology
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CRT Nonresponders Experience Poor Outcomes, Warrant More Aggressive Management
The ADVANCE CRT registry revealed a significant minority of patients fail to respond to cardiac resynchronization therapy, conferring a worse prognosis.
Is the Physical Exam an Anachronism in Heart Failure?
In the PARADIGM-HF trial, signs of congestion during physical exam were related to outcomes and the improved outcomes observed with valsartan/sacubitril vs. enalapril.
CABG vs. PCI for Left Main Disease at 5 Years
Five years after randomizing 1,905 patients with left main disease to coronary artery bypass grafting or percutaneous coronary intervention, researchers found no significant difference in the primary composite outcome of death, stroke, or myocardial infarction.
Why Was There Syncope?
The 12-lead ECG in the figure was obtained from a middle-aged woman with syncope and hypotension but no chest pain. No long lead rhythm strip is available. What might be causing her syncope?
Omeprazole Magnesium, Amoxicillin, and Rifabutin Delayed-Release Capsules (Talicia)
Talicia is indicated for the treatment of Helicobacter pylori infection in adults.
Urine Cultures: A Gateway to Antibiotic Overuse
Inappropriate antibiotics use in nursing homes across North America continues driving antibacterial resistance and the risk of Clostridioides difficile infection in the elderly.
Consensus Position Statement on the Use of Testosterone in Women
A task force of representatives from leading international societies issued guidance for appropriate prescribing of testosterone in women.
Sexually Transmitted Diseases in the United States — Not a Happy Picture
Since reaching historically low rates, many sexually transmitted infections have re-emerged in the United States. Of particular concern is the continued emergence of antibiotic resistance in Neisseria gonorrhoeae.
Optimism (Hopefully!) Increases Odds of ‘Exceptional Longevity’
Analysis of 10-year follow-up data from the Nurses’ Health Study and 30-year follow-up data from the Veteran Affairs Normative Aging Study show a significant association between baseline levels of higher optimism and longevity, even when data is adjusted for health behaviors and psychosocial factors.
Soft Drinks and Death
This long-term, large-scale European study finds that higher use of total soft drinks is associated with a higher risk of death; additionally, higher use of artificially sweetened soft drinks is associated with higher risk of death from cardiovascular illness and higher use of sugar-sweetened soft drinks is associated with higher risk of death from digestive illnesses.