Cardiology
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2019 Community-Acquired Pneumonia in Adults Guideline: Not Much New Under the Sun
One can quibble over a number of the guideline recommendations, but they provide a valuable touchstone for clinical management of patients with community-acquired pneumonia, despite the fact that so many of the recommendations are based on low- or very low-quality evidence.
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Mortality and Vitamin D Supplementation: A Meta-Analysis
Researchers determined that when compared with placebo or no treatment, vitamin D supplementation alone was not associated with an increase in overall all-cause mortality, although there were some nuances based on vitamin D form and type of mortality.
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Iron Absorption in Iron Deficiency Anemia With Alternate-Day Dosing
In a cohort of 19 women with iron deficiency anemia, alternate-day doses of iron led to 40-50% more iron absorption compared to consecutive-day doses.
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Is This Acute?
There is a stack of ECGs in need of interpretation. The tracing in the figure is among those tracings. No clinical information is available. How would one interpret this ECG? Are the changes acute?
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Trifarotene Cream (Aklief)
Trifarotene should be prescribed for the topical treatment of acne vulgaris in patients ≥ 9 years of age.
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Ginkgo Benefits for Tinnitus?
Twelve weeks of twice-daily Ginkgo biloba extract improved symptoms as effectively as pentoxifylline in 200 adults with chronic tinnitus.
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Effects of Probiotics on Cognition and Fall Risk in Patients With Cirrhosis
Patients with cirrhosis and mild cognitive impairment and falls were randomized to a probiotic formulation vs. placebo. Probiotic treatment improved cognitive outcomes and reduced the risk of falls.
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Is It Safe to Stop Digoxin for Heart Failure?
In a large older patient heart failure with reduced ejection fraction hospitalizations database, the outcome of withdrawing digoxin vs. continuing digoxin was examined at 30 days and up to four years of follow-up. Withdrawing preadmission digoxin in hospital resulted in higher mortality at 30 days and more readmissions at six months, one year, and four years.
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Predictors of Response to a Specific Psychological Treatment in Chronic Low-Back Pain
A theoretical model employed to predict response to either mindfulness meditation, cognitive therapy, or mindfulness-based therapy in patients with chronic low-back pain showed evidence that this type of model may be useful in determining which patients are most likely to benefit from a specified intervention.
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Effects of Probiotics on Cognition and Falls Risk in Patients With Cirrhosis
Patients with cirrhosis and mild cognitive impairment and falls were randomized to a probiotic formulation vs. placebo. Probiotic treatment improved cognitive outcomes and reduced the risk of falls.