Cardiology
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Clostridioides difficile Infection: Fecal Microbiota Transplantation vs. Antibiotics
Relative to vancomycin or metronidazole treatment of recurrent Clostridioides difficile infection, treatment with fecal microbiota transplantation is associated with a lower risk of bloodstream infection, shorter hospital length of stay, and improved survival.
Dual Antiplatelet Therapy Increases Serious Hemorrhages Following TIA or Minor Stroke
Caution should be taken and close observation of patients maintained when treating with dual antiplatelet therapies.
Soft Drinks and Death
Investigators found drinking more soft drinks, both artificially sweetened and sugar-sweetened, is associated with a higher risk of death, cardiovascular illness, and digestive illnesses.
Airplane-Triggered Headaches
Severe, unilateral headaches that occur during airplane travel, particularly during landing, are most likely a variant of migraine headaches triggered by changes in cabin pressure.
When to Administer the 13-Valent Pneumococcal Conjugate Vaccine: A Review of the ACIP Recommendations
Recently revised guidelines no longer recommend the 13-valent pneumococcal conjugate vaccine for most healthy adults.
Seven Days of Antibiotics Was Noninferior to 14 Days for Gram-Negative Rod Bacteremia
In patients with gram-negative rod bacteremia, patients receiving seven days of antibiotics had similar 90-day mortality, readmission rates, and rates of recurrent bacteremia as patients receiving 14 days of antibiotic.
Balanced Crystalloids Reduce Mortality in Critically Ill Adults With Sepsis or Septic Shock
Compared to saline, balanced crystalloids reduced in-hospital mortality and major adverse kidney events within 30 days in critically ill patients with sepsis or septic shock.
The Epidemic of Vaping-Associated Lung Injury
Since June 2019, there has been a considerable rise in reported cases of vaping-associated lung injury.
Predicting the Progression of Chronic Aortic Regurgitation
A large database observational study of patients with chronic aortic mild or moderate regurgitation (AR) largely due to bicuspid aortic valve or aortic root dilatation showed that it was largely an indolent disease, with only 20% progressing to moderately severe AR in five years.
Perioperative Management of Direct Oral Anticoagulants
A simple protocol for managing atrial fibrillation patients on direct oral anticoagulants perioperatively was shown to produce low levels of major bleeding and thromboembolism for 30 days postoperatively.