Cardiology Topics
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Long-Term Statin Use Associated with Lower Stroke Risk
A cohort of Danish patients who were taking the cholesterol control medication were less likely to experience an intracerebral hemorrhage.
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Apixaban for Venous Thromboembolism in Patients with End-Stage Kidney Disease
There is a lower risk of bleeding for those taking apixaban during venous thromboembolism treatment compared to warfarin in patients with end-stage kidney disease.
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Is Routine Stress Testing After Coronary Revascularization Necessary?
A multicentered study of routine stress testing at one year post-percutaneous coronary revascularization compared to usual care in patients with at least one high-risk coronary anatomic or clinical feature failed to show improved clinical outcomes at two years follow-up.
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The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.
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Is Illicit Substances Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.
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Periodontal Disease as an Independent Risk Factor for Cardiovascular Disease
Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.
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The Clue in Lead II
How should one interpret the ECG in the figure? The figure was obtained from a 40-year-old man who was hemodynamically stable at the time this tracing was recorded. The key clue is in lead II.
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Mitral Transcatheter Edge-to-Edge Repair Gains Traction in Cardiogenic Shock Patients
The authors of this large registry study examined transcatheter edge-to-edge repair in patients with cardiogenic shock and severe mitral regurgitation (MR). Successful repair was achievable in most patients and was associated with lower mortality rates and heart failure hospitalization at one year.
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Triglyceride-Lowering Therapy and Cardiovascular Events
Researchers studied pemafibrate vs. placebo in patients with type 2 diabetes, mild-to-moderate triglyceride elevations, and low levels of HDL and well-controlled LDL cholesterol. Despite a 31% reduction in triglyceride levels, there was no improvement in the risk of cardiovascular outcomes over a median follow-up of 3.4 years.
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Is It Better to Up-Titrate Medications Faster in Acute Heart Failure Patients?
Early intensive up-titration of guideline-recommended therapy in patients admitted for heart failure reduced 180-day readmission and all-cause mortality at the cost of more adverse events (but not serious or fatal ones).