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Nitrate Tolerance: Can Studies of Vascular Biology Resolve the Conundrum?

Mechanical Chest Compressions in CPR

Effective cardiopulmonary resuscitation (CPR) is partly dependent on the adequacy of manual chest compressions, but they are limited by interruptions and less than ideal conditions such as during transport.

Risk of Early Repolarization ECG Patterns

ECG early repolarization patterns were long thought to be benign normal variants until recent papers purported to show a relationship between these patterns and the risk of malignant arrhythmias and cardiac death.

Prognosis of Ventricular Fibrillation in Acute Myocardial Infarction

At this time, ventricular fibrillation (VF) early after acute myocardial infarction (MI) is not an indication alone for an implantable cardioverter-defibrillator (ICD) therapy.

Management of Severe Ischemic Mitral Regurgitation

Practice guidelines recommend mitral valve repair or replacement for severe ischemic mitral regurgitation (MR) that is causing symptoms refractory to best available medical therapy.

Are Implanted Defibrillator Therapies Deactivated at End of Life?

This study aimed to determine the incidence of appropriate shocks, inappropriate shocks, and device malfunction prior to death in patients with implantable cardioverter-defibrillators (ICDs).

Prognosis of First-Degree AV Block

Although long believed to be benign, first-degree AV block has recently been shown to be associated with atrial fibrillation development, pacemaker need, and all-cause mortality.