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Patients with diabetic polyneuropathy or postherpetic neuralgia were randomized to receive one of three sequences of daily oral gabapentin, nortriptyline, and the combination of both drugs in a double-dummy, double-blind, crossover study.
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Radical hysterectomy remains the primary surgical procedure of choice for women with early-stage cervix cancer because of its ability to remove the primary site and surrounding tissues, which help to classify risk for recurrence and in some cases, indicate adjuvant therapy.
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Currently, there is no consensus on how to screen for CMV, a problem that affects about 1% of pregnancies in the United States.
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In a retrospective tumor registry (SEER) analysis of outcomes for rectal-cancer patients treated over a 14-year period with either presurgical or postsurgical radiation therapy, the importance of pathological lymph node status was found to be significantly more adverse for patients who had presurgical treatment. These patients define a subgroup for whom aggressive post-surgical treatment would seem warranted.
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Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
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This meta-analysis revealed overall increased mortality of up to 25% in patients experiencing depressive symptoms after cancer diagnosis, and a 39% higher risk in patients diagnosed with major or minor depression after cancer diagnosis, based upon 25 independent studies. Given the low number of studies available to date, the effect of depressive symptoms on cancer recurrence did not reach a level of statistical significance.
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In a large population-based, prospective cohort study, it was found that spending less than 50% of the day in a sedentary position, and increasing amounts of physical activity (e.g., walking or bicycling) appear to be associated with reduced rates of prostate-cancer development.
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A long-term longitudinal assessment of quality of life among patients treated for early-stage Hodgkin's lymphoma reveals that, with the exception of fatigue, there is general improvement over time. Factors that influence the rate of improvement include age and sex, but do not include the type of treatment received (radiation vs. chemotherapy).
