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Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
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Four large data sets were analyzed to evaluate the effect of adjuvant treatment on survival in patients with stage III colon cancer diagnosed after age 75. While adjuvant chemotherapy was associated with a survival benefit, oxaliplatin-based regimens offered no more than a small incremental benefit over non-oxaliplatin-containing regimens.
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In this case-control study, dietary lignan intake was inversely associated with risk of breast cancer in both premenopausal and postmenopausal women. Also noted were more favorable prognostic characteristics associated with lignan intake, especially in premenopausal women.
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A 78-year-old female had been generally well with no known chronic medical conditions and was taking no medications when she presented to her primary care physician with lower abdominal pain and urinary frequency of one month's duration. Physical examination at the time revealed a well-appearing woman with normal vital signs and no abnormal physical findings except a palpably enlarged uterus by bimanual pelvic examination. CT scan confirmed the presence of a uterine mass suspicious for malignancy. She was referred to a gynecologic oncologist and had a total abdominal hysterectomy and salpingo-oophorectomy with partial infracolic omentectomy and pelvic debulking of what appeared to be a large (15 cm) tumor mass. Final pathology was high-grade leiomyosarcoma with microscopic invasion of the colon and bladder.
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The authors assessed the risk of venous thrombosis (vt) in current users of non-oral hormonal contraception using four national registries in Denmark.
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Gestational diabetes (gdm) now complicates about one in 15 pregnancies, but, undoubtedly, the prevalence will increase even further if we cannot curb the concerning rise in obesity in this country.
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You've seen her before. she's often young and partnered, but might be midlife and changing the status of her relationship. Sometimes she presents for an annual exam and mentions her pain later during the visit. Occasionally she actually presents with the complaint of dyspareunia.
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The authors sought to estimate trends in prenatal drug exposure and neonatal abstinence syndrome (NAS) in Washington State from 2000 to 2008.
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Is azithromycin proarrhythmic? Macrolide antibiotics are associated with an increased risk of sudden cardiac death, but azithromycin (Zithromax), the popular "Z pack" macrolide, has been considered safe.