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Light-exacerbated pain occurring during migraine headaches is associated with increased cerebral blood flow in the visual cortex. This activation of retinal ganglion cells by light, present even in blind migraineurs, occurs through posterior thalamic connections.
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Impulse control disorders in Parkinson's disease are associated with a unique pattern of electrophysiological activity in the ventral subthalamic nucleus.
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Apixaban and rivaroxaban near approval for nonvalvular atrial fibrillation; fidaxomicin for C. difficile infections; guideline for intensive insulin therapy; and FDA Actions.
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Therapeutic hypothermia does not result in improved outcomes in patients with traumatic brain injury.
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The Health Improvement Network UK Primary Care Database was queried for all patients aged 50-84 who were prescribed low-dose aspirin (75-300 mg/day) for the secondary prevention of cardiovascular disease in 2000-2007.
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Twenty highly active patients with neuromyelitis optica (NMO) stabilized after treatment with mitoxantrone. All patients tolerated treatment without significant safety concerns. Mitoxantrone may be an option for NMO given its differential inhibitory effect on subsets of B-cells.
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Early plasmapheresis and high-dose intravenous corticosteroids may be as effective as conventional oral corticosteroid therapy in the treatment of myasthenia gravis.
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The applause sign is a nonspecific indicator of frontal lobe dysfunction and is not specific to Parkinsonian disorders.
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A novel technique used to study deviations in the subjective visual vertical may assist in the localization of brainstem lesions.
