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Inhaled apomorphine, at doses up to 0.8 mg, appears safe and well tolerated by patients with Parkinson's disease, but does not result in significant improvement in wearing "off" periods, at the tested doses.
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Utilization of continuous EEG monitoring in mechanically ventilated patients in the ICU was associated with a reduction in hospital mortality without significantly affecting hospital costs or length of stay.
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In young children with myasthenia gravis, height and bone age are negatively impacted by chronic corticosteroid usage, but not by thymectomy.
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In a large histopathological study, the distribution of nonheme iron and the expression of iron-related proteins in multiple sclerosis (MS) brains were compared to controls.
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Although never confirmed in a randomized clinical trial, thymectomy appears to be efficacious in children with antibody-positive myasthenia gravis.
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In this 12-week, randomized, double-blind and double-dummy trial, intrajejunal infusion of levodopa-carbidopa gel decreased "off" time by almost 2 hours more than oral levodopa-carbidopa in individuals with Parkinson's disease suffering motor fluctuations.
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Current trials with amyloid antibodies have not shown clinical benefit, but the results suggest that treating patients earlier in the course, or during the presymptomatic period, might be beneficial.