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Patients with spinal epidural abscess may be normothermic and have normal WBC counts. Urgent surgery was more likely to be offered to patients presenting with neurologic deficits than with pain alone. Patients treated without early surgery were significantly more likely to deteriorate and suffer poor outcomes.
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It is recognized that most cases of chronic tinnitus are generated by central brain mechanisms that may be amenable to treatment with cognitive therapies and magnetic stimulation protocols of the temporal and frontal lobes.
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Normal pressure hydrocephalus remains a clinical diagnosis and standardized clinical assessments predict a positive response to shunting in most patients.
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Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
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Changes in CSF metabolites reflect dopamine and norepinephrine deficiency in Parkinson's disease, and may be sensitive in early identification.
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Over a 6-year period, 2305 patients with reduced left ventricular ejection fraction and normal sinus rhythm were randomized to warfarin treatment (target INR of 2.0 to 3.5) or aspirin (325 mg per day) and followed to determine the rate of a composite endpoint of ischemic stroke, intracerebral hemorrhage, or death from any cause.
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Primary progressive apraxia of speech has been well characterized as a distinct neurodegenerative disease, but underlying pathology and prognosis are uncertain in most cases.
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Clinical examination severity appears to be the best predictor of response to immunotherapy in patients with myasthenia gravis.
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Lorcaserin for weight loss; statins and fatigue; treatment-resistant gonorrhea; hydrocodone classification changes; USPSTF recommendations; and FDA actions.