Bacterial Infections
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Virtual Visits and Antibiotic Prescribing
Compared to in-person visits, virtual visits were associated with improved antibiotic prescribing practices for women with uncomplicated urinary tract infections.
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Honey, Can You Stop Coughing?
Since there is little to offer those with upper respiratory infections, honey represents a low-risk, inexpensive, and easily accessible alternative that seems reasonable to suggest to patients.
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A Novel Rifabutin-Containing Combination Regimen Eradicates H. pylori Infection
Researchers found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.
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Antibiotic Use in COVID-19 Patients
Fifty-seven percent of patients with COVID-19 infection treated at 38 hospitals in Michigan received early empiric antibiotics, although researchers documented community-onset bacterial coinfection in only 3.5%.
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HHS Releases Latest Iteration of Antibiotic Resistance Action Plan
The five-point strategy crafted in previous years remains the same, but the tactics have improved to help execute the goals. The new plan includes details about stronger and more evidence-based activities that have reduced antibiotic resistance that public health officials can lean on to drive progress.
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Should Metronidazole Be Added Routinely to Treatment Regimens for PID?
This randomized, double-blind, placebo-controlled trial compared ceftriaxone (250 mg intramuscular once) and doxycycline (100 mg orally twice per day for 14 days) with and without metronidazole (500 mg orally twice per day for 14 days) for the treatment of pelvic inflammatory disease.
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A New Treatment for Recurrent Bacterial Vaginosis?
Recurrent bacterial vaginosis is a problem that affects many women, with an estimated 50% of women developing a recurrence within 12 months of treatment. The authors of this study tested the efficacy of a novel product, Lactobacillus crispatus CTV-05 (Lactin-V), in reducing bacterial vaginosis recurrence in this phase 2b clinical trial.
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Investigators Identify Connection Between Vascular Malformation, Gut Bacteria Profile
The presence of gram-negative bacteria was linked to an abundance of abnormalities known to cause strokes, seizures, and headaches.
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Empiric Anti-MRSA Therapy in Pneumonia May Not Always Be a Good Idea
In a retrospective cohort study, empiric anti-methicillin-resistant Staphylococcus aureus treatment was not associated with a reduction in mortality in any subgroup of patients studied and appeared to cause harm in many.
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Clindamycin Improves Outcomes in Necrotizing Fasciitis Due to Group A Streptococcus
Using a murine model of necrotizing fasciitis, investigators determined that clindamycin inhibits key virulence factors of Group A Streptococcus, and should be given as soon as possible and at high doses to reach levels above MIC in affected tissues.