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In this issue: Drug combinations for hypertension; tenecteplase for
out-of-hospital cardiac arrest; CAM most commonly used for back, neck, and
arthritis pain; FDA Actions.
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Since 1993, clinical isolates of s. pneumoniae from normally sterile sites, including middle ear cultures, have been prospectively obtained from the Texas Children's Hospital clinical microbiology laboratory, and stored frozen.
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Accurate microbiologic diagnosis of prosthetic joint infection (PJI) is problematic. Infecting organisms reside in a biofilm, and standard culture techniques appear to have sub-optimal sensitivity.
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In a study designed to evaluate potential methods for improving survival by prevention of infection in ICU patients, de Smet et al used cluster randomization involving 13 centers in the Netherlands, with assignment to one of three treatment arms: selective decontamination of the gastrointestinal tract (SDD), selective oropharyngeal decontamination (SOD), or standard of care (SOC).
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Concerns have been raised that immigrants, especially those who are undocumented, afraid of deportation or who have limited financial resources, may be reluctant to present for care, thus compounding the risk for contagious diseases.
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Patients enrolled in the swiss hiv cohort study, initiating their first cART regimen between 1996 and early 2007, who had baseline and follow up CD4+ count and HIV RNA data available, were included in the analysis.
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Most of us microbiologists were rudely awakened to the insufficiency of our susceptibility testing methods last year when the College of American Pathologists (CAP) sent out a carbapenemase-producing Klebsiella pneumoniae as an unknown proficiency testing sample. My laboratory, like most others in the United States, incorrectly reported the isolate as susceptible to imipenem and meropenem.
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An outbreak of 140 human cases of West Nile Virus in Kern County, California (better known for its increased risk of coccidioidomycosis), during the summer of 2007, prompted Reisen et al to look for possible causes.
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