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Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
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The risk of interrupting prophylactic warfarin for stroke prevention in atrial fibrillation (AF) patients is unclear. Thus, these investigators from Denmark evaluated their national health registry and found 102,591 patients > age 30 with a first-time hospitalization for AF between 1997 and 2008.
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In patients with stable coronary artery disease (CAD), medical therapy is the mainstay of treatment. Percutaneous coronary intervention (PCI) guided by angiographic stenosis is more effective than medical therapy at reducing angina, but does not change the rate of death or myocardial infarction (MI).
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Patients with chronic kidney disease or who have had renal replacement therapy have often been excluded from trials of anticoagulation in atrial fibrillation (AF). In this study, the authors analyzed data from hospitalized patients with nonvalvular AF in Denmark from 1997 through 2008. Patients with chronic kidney disease with and without renal replacement therapy were identified from a national registry.
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In the setting of acute ST segment elevation myocardial infarction (STEMI), warfarin is indicated for atrial fibrillation, a large dyskinetic or aneurysmal area of the left ventricle, or mural thrombus.
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Patients presenting to the emergency department (ED) with chest pain are often admitted to "rule out" myocardial infarction (MI). Many of the patients are subsequently found to have noncardiac causes of chest pain.
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Some patients who experience stroke or transient ischemic attack (TIA) of unknown cause (i.e., cryptogenic) are subsequently found to have a patent foramen ovale (PFO).
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The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Study compared two doses of dabigatran, a direct thrombin inhibitor, with warfarin for the prevention of stroke and systemic emboli in patients with nonvalvular atrial fibrillation (AF).