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The catheter ablation versus antiarrhythmic Drugs for Atrial Fibrillation (A4) study compared radio-frequency catheter ablation to antiarrhythmic therapy in selected patients with paroxysmal atrial fibrillation (PAF).
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The resynchronization reverses remodeling in Systolic Left Ventricular Dysfunction (REVERSE) trial tested the hypothesis that cardiac resynchronization therapy (CRT) would benefits patients with New York Heart Association (NYHA) functional class I and II heart failure and a prolonged QRS duration.
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Optimal management of transmural myocardial infarction (MI) depends on rapid reperfusion of the occluded infarct artery.
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Diabetics are known to have higher rates of restenosis after revascularization than non-diabetic subjects.
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The ACC/AHA guidelines recommend perioperative beta blockers for those already on them, patients undergoing vascular surgery, or those having intermediate- to high-risk surgery with established coronary heart disease, or at high risk of having it.
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Percutaneous intervention for peripheral arterial disease (PAD) results in improvement in claudication symptoms but is complicated by a high rate of restenosis.
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Low-flow, low-gradient aortic stenosis (AS) is usually associated with reduced left ventricular (LV) performance. When LV systolic function is normal, it has been labelled paradoxical.
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Transesophageal echocardiography (TEE) is commonly performed prior to atrial fibrillation (AF) ablation to exclude left atrial appendage thrombus.
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Although carotid artery stenting (CAS) is a less invasive means of carotid revascularization, multiple trials have demonstrated an increased risk of post-procedural stroke in patients with symptomatic carotid stenosis, as compared to carotid endarterectomy (CEA).
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Symptomatic left ventricular outflow tract (LVOT) obstruction is common in patients with hypertrophic obstructive cardiomyopathy (HOCM), and medical therapy does not always relieve the symptoms. In such cases, septal reduction therapies are indicated, and both alcohol septal ablation (ASA) and surgical myectomy have been proven to reduce symptoms effectively.