Anticoagulation/Thromboembolism
RSSArticles
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Comparison of Postoperative Antibiotic Regimens for Complex Appendicitis
In a pragmatic, open-label, randomized trial conducted at 15 hospitals in the Netherlands, two days of postoperative intravenous antibiotics for complex appendicitis was found to be noninferior to five days in terms of infectious complications and mortality within 90 days.
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DOACs Can Safely Be Started Early After Atrial Fibrillation-Associated Stroke
In ischemic stroke associated with atrial fibrillation, early restart of anticoagulation with apixaban one to three days after ischemic stroke, compared to late restart (seven to 14 days), resulted in no significant differences between the groups in the primary outcome — a composite endpoint including recurrent ischemic stroke, symptomatic intracranial hemorrhage, and systemic embolism.
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Anticoagulated Trauma Patient
Emergency medicine providers commonly encounter anticoagulated trauma patients, and it is essential to understand the critical aspects of caring for this unique subpopulation, including specific traumatic injury patterns, emergent reversal, and surgical considerations, as well as relevant emerging concepts.
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Pulmonary Embolism
Emergency clinicians need to remain updated on the management and treatment of many critical diagnoses. Pulmonary emboli carry a significant morbidity and mortality, even with the advances in treatment that have been made over the past several decades. Having a high suspicion, making the diagnosis early, and initiating treatment are important for optimal patient outcomes.
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Oral Anticoagulation Falls Short as Default Treatment Post-TAVR
In patients without an indication for anticoagulation undergoing transcatheter aortic valve replacement, treatment with edoxaban did not significantly affect the incidence of leaflet thrombosis as detected by CT scans.
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Gastrointestinal Bleeding on Anticoagulants: Predicting Colorectal Cancer in Afib Patients
A large Danish registry study showed that in atrial fibrillation patients on oral anticoagulants and who experience a lower gastrointestinal bleed, the incidence of a subsequent diagnosis of colorectal cancer is significantly higher than in those without bleeding.
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Intensive Monitoring for Asymptomatic Atrial Fibrillation Did Not Prevent Strokes
Screening with an implantable loop recorder resulted in dramatically higher rates of atrial fibrillation detection and ensuing anticoagulation, but without a significant decrease in risk of stroke or systemic embolism by six years of follow-up.
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Pharmacotherapy for Atrial Fibrillation with Anticoagulation-Associated Intracranial Hemorrhage
A study of apixaban vs. no anticoagulation in patients following an anticoagulant for atrial fibrillation-related intracerebral hemorrhage exhibited a high risk of stroke and vascular death, regardless of whether the patients were treated subsequently with apixaban.
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Aspirin, Clopidogrel, or Both After Coronary Interventions?
A recent study of patients who had undergone a percutaneous coronary intervention and were transitioning from dual antiplatelet therapy to monotherapy showed clopidogrel was superior to aspirin for preventing further major adverse events, including bleeding. -
Mixed News for Lung Health
Deaths from lung cancer are on the decline, while deaths from lung clots are on the rise, according to a pair of new reports.