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A clinical trial involving school-aged children in Thailand shows that a tetravalent dengue vaccine is safe and immunogenic, despite frequently bothersome side effects.
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Zoonotic transmission resulting from exposure to infected cats was responsible for an epidemic of 178 human cases of sporotrichosis in Rio de Janeiro, Brazil, from 1998 to 2001. Cats infected with sporotrichosis pose a significant risk of disease transmission to humans because of their extensive skin lesions and high burden of organisms.
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The National Cholesterol Education Program (NCEP), a product of a collaboration of the National Heart, Lung, and Blood Institutes, the American College of Cardiology, and the American Heart Association, has updated its clinical practice guideline on cholesterol management.
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The benefit of ICD therapy, compared to amiodarone therapy in patients with life-threatening arrhythmia, continues to increase over time, and long-term data support the use of an ICD as first line therapy for secondary prevention of sudden cardiac death.
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Annual, or less frequent, surveillance intervals are effective for aneurysms < 45 mm in diameter.
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Symptoms that are more severe or frequent than expected and of recent onset warrant further diagnostic investigation because they are more likely to be associated with both benign and malignant ovarian masses.
