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Enalapril improves effort tolerance and reduces dyspnea in patients with symptomatic aortic stenosis, but may cause hypotension in those with congestive heart failure, left ventricular dysfunction, or systolic blood pressure < 100 mm Hg.
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The AFFIRM study was a randomized comparison of 2 strategies for management of patients with atrial fibrillation. Patients with atrial fibrillation requiring therapy, who also had one or more risk factors for stroke or death, were randomized to either a rate control strategy of cardioversion and treatment with antiarrhythmic drugs or a rate control strategy using atrioventricular (AV) nodal blocking agents to control ventricular response. Results of this study suggest that if an effective method for maintaining sinus rhythm with fewer adverse effects were available, it might improve survival.
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The FDA has approved another rapid-acting insulin to cover mealtime blood sugar spikes.
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Seizures should be a red flag to consider treatment to modify stroke risk.
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In this cross-sectional population based study from California, it is apparent that screening is currently applied to older women without consideration of health status.
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This is a fascinating report of a cluster of human Plasmodium knowlesi cases misdiagnosed as Plasmodium malariae in a rural rainforest area of Sarawak.
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Despite some initial controversy, it appears that HIV-infected patients with relapses of visceral leishmaniasis have higher levels of HIV-RNA viral loads and lower CD4+ counts than those without relapses. Non-compliance with HAART regimens and intravenous drug use possibly contribute to this greater risk of relapse.
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On April 5, 2004, Aventis Pasteur contacted all recipients of IMOVAX Rabies Vaccine to inform them of an urgent recall of their manufactured lots: X0067-2, X0067-3, W1419-2, and W1419-3.