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Erythema Multiforme (EM), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a spectrum of a single disease that share common causes and mechanisms but are differentiated based on the severity of the reaction. They are relatively rare in occurrence, but are associated with significant mortality rates.
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An increase in coxsackie b-1 virus (CVB-1) infections was observed in 2007 in the United States, associated with an increase in neonatal cases and multiple deaths.
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Cain et al analyzed the cases of tuberculosis that occurred in the United States among foreign-born persons from 2001-2006.
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Legionella spp. are gram-negative bacteria found primarily in freshwater environments; they cause disease (including outbreaks) often linked to man-made water systems.
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In the Issue: Ongoing safety review of tiotropium; raloxifene reduces the risk of endometrial cancer; one-day treatment with famciclovir may be as effective as 3-day treatment with valacyclovir; new Clinical Practice Guideline from the American College of Physicians regarding pharmacologic treatment for low bone density and osteoporosis; FDA Actions.
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An 18-year-old man from togo was admitted to a hospital in Sweden with a three-day history of chest, stomach, and back pain, with recurrent episodes of sweating and fever.
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Many physicians have followed the historical practice of ordering blood cultures to be drawn as close as possible to the time of the peak of the febrile episode (fever spike).
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Of 583 children < 18 years of age tested for anti-neutrophil cytoplasmic antibody (ANCA) at Boston Children's Hospital from 1996 to 2006, 27 children had a history of minocycline administration, with clinical and laboratory findings of autoimmunity. Of these 27 children, 19 were female (70%).