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Clinical Briefs in Primary Care supplement
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Tetracycline and T-cell Activation
CD4+ t cells were obtained from HIV-negative donors and HIV-positive patients receiving HAART with suppressed viremia. Using a single-cycle replication system and an X4 pseudovirus used to infect cells, minocycline, at concentrations from 0-50 ug/mL, demonstrated a dose-dependent reduction in the percentage of infected cells. -
Microbial Translocation and HIV Infection
Twenty-one patients with HIV-1/AIDS, seven patients with hiv-2/aids, 43 patients with HIV-1 chronic infection, and 66 patients with HIV-2 chronic infection in Guinea-Bissau were studied along with 66 HIV-negative policemen. -
Pharmacology Watch: Atypical Fractures and Bisphosphonate Therapy
In this issue: Fractures and bisphosphonate therapy, warfarin anticoagulation and influenza vaccine and cotrimoxazole, antiplatelet therapy with clopidogrel and aspirin, FDA Actions. -
Infectious Disease Alert June 2010 Issue in PDF
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Updates by Carol A. Kemper, MD, FACP
These authors assessed the benefits of antiviral therapy of the index flu patient on reduced viral shedding and prevention of secondary household cases who did not receive chemoprophylaxis. -
Pharmacokinetic, Pharmacodynamic, and Clinical Efficacy of Continuous or Extended Infusion Regimens of Piperacillin/Tazobactam
Piperacillin/Tazobactam (P/T) offers one of the broadest antimicrobial spectrums, and is equipped with an effective mechanism to maintain its potency in the presence of beta-lactamases. -
Emergency Medicine Reports - Full May 24, 2010 Issue in Streaming Audio/Downloadable MP3 Format
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Emergency Medicine Reports - Full May 24, 2010 Issue in PDF
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ED, researchers learn to co-exist
In most EDs, the last thing a provider wants is an extra, non-clinical individual "getting in the way."