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Postinfectious Irritable Bowel Syndrome
Some patients seem to develop chronic irritable bowel syndrome following an episode of gastroenteritis, possibly based on excessive mucosal serotonin release. -
Effects of a New Aldosterone Blocker in Patients with Myocardial Infarction
The addition of eplerenone to optimal medical therapy reduces morbidity and mortality among patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure. -
Full June 16, 2003, Issue in PDF
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Clinical Briefs in Primary Care Supplement
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Full September 2003 Issue in PDF
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Pharmacology Watch: Study Shows Oral IIb/IIIa Receptors Increase Mortality
Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist. -
Ultrasound Evaluations of Cervical Length in Preterm Labor
In women with threatened preterm labor, sonographic measurement of cervical length helps distinguish between true and false labor. -
Fetal Assessment Comparing Nonstress Test with Umbilical Artery Doppler Velocimetry
Umbilical artery Doppler as a screening test for fetal well-being in a high-risk population was associated with a decreased incidence of cesarean delivery for fetal distress compared to the nonstress testing, with no increase in neonatal morbidity. -
12 vs 3 Months of Maintenance Paclitaxel in Patients with Advanced Ovarian Cancer after Platinum and Paclitaxel-Based Chemotherapy
Twelve cycles of single-agent paclitaxel administered to women with advanced ovarian cancer who attain a clinically defined complete response to initial platinum/paclitaxel-based chemotherapy significantly prolongs the duration of progression-free survival. -
Postmenopausal Hormone Therapy and Coronary Heart Disease
The WHI and the WELL-HART clinical trials report that hormone therapy does not reduce the risk of coronary events or slow the progression of atherosclerosis in older women.