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A Negative Nares Screen for MRSA Helps Exclude MRSA Pneumonia
A meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia. MRSA nasal screening can be a useful tool for antimicrobial stewardship personnel to de-escalate empiric anti-MRSA therapy.
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Are In-hospital Deaths Related to Community-acquired Pneumonia Preventable?
This secondary analysis of data from five tertiary care centers found that among patients hospitalized for community-acquired pneumonia, very few deaths potentially were related to a lapse in in-hospital quality of pneumonia care.
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Neighborhood Socioeconomic Status Associated With Infection Risk, But Not Sepsis
Based on a large, national, prospective cohort study, lower neighborhood socioeconomic status was associated with a higher incidence of hospitalizations for infection (but not sepsis) at presentation.
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Post-intensive Care Syndrome: What Happens After the ICU?
The number of ICU patients admitted annually continues to grow, with most recent estimates reaching 5.7 million. As there are growing numbers of critically ill patients, sepsis survivorship also has grown as a substantial public health concern, with a significant number of survivors diagnosed with post-intensive care syndrome (PICS). It is important to go beyond saving lives in the ICU and devote additional time and attention to preventing and treating the psychiatric, cognitive, and physical sequalae of ICU illness in the follow-up setting.
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Avatrombopag Tablets (Doptelet)
Doptelet is prescribed for adults with thrombocytopenia and chronic liver disease who are scheduled to undergo a medical procedure.
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‘The World Is Covered by a Thin Layer of Feces’
This study mirrors earlier work in New York City, which found that sand boxes and dog play areas often are contaminated with C. difficile.
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Oral Antibiotics May Increase the Risk for Nephrolithiasis
A case-control study found that receipt of an oral antibiotic in the preceding three to 12 months was associated with nephrolithiasis. The risk persisted up to five years, and younger patients were at increased risk.
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Does Childhood Adversity Affect the Menopausal Transition?
The number and timing of adverse childhood experiences in relation to puberty affect the risk of incident major depressive disorder in menopausal transition.
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Simple Prediction Tool Facilitates Diagnosis of Heart Failure With Preserved Ejection Fraction
In patients with unexplained dyspnea, a score based on six noninvasive criteria can predict the likelihood of heart failure with preserved ejection fraction.
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Emergency Clinicians Steer Patients With Substance Use Problems Into Effective Treatment
Baltimore has struggled mightily with substance misuse, and much of this burden has fallen on EDs in the region. This has prompted hospitals and public health authorities to create innovative solutions to address the problem in a comprehensive way.