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Predicting the Risk of Mild Cognitive Impairment Using Imaging Biomarkers
In this population-based study, researchers used imaging biomarkers of amyloid and neuronal injury to estimate an absolute risk of mild cognitive impairment in the elderly.
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Late Referrals to Hospice Continue, Due Largely to ‘Fear and Stigma’
Despite emphasis on the importance of early referral, patients with advanced disease are receiving palliative care very late in their illness trajectory, found a recent study from the United Kingdom.
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Amyloid-ß Pathology Induced by Contaminated Cadaver-Derived Growth Hormone
Cadaveric pituitary-derived growth hormone that previously was known to transmit Creutzfeldt-Jakob disease (CJD) also contains ß-amyloid. Growth hormone vials from cases associated with amyloid plaques in CJD patients cause amyloid plaque formation and cerebral amyloid angiopathy when injected intracranially into mice.
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Ethics of Genomics Consent: Little Is Known on This Issue
To learn where things stand on individuals’ views on privacy and genetic data, researchers analyzed 53 studies involving the perspectives of 47,974 participants.
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Rituximab for CIDP Associated With Systemic Immune Disorders
Rituximab has been used “off label” for the treatment of primary chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with variable reports of success. These authors reported a high rate of response in patients who developed CIDP in the setting of other systemic immune-mediated disorders.
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Ethical Concerns With Quality Ratings of Nursing Homes
Quality ratings of nursing homes are not necessarily what they seem, according to a recent analysis.
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Ethics of Genetic Research on Alcohol Addiction
Genetic testing is not yet ready for use in the prediction of alcohol dependence, according to a recent ethical guidance.
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Revised Guidelines, New Data Shed Light on Palliative Care
While hospice care is a Medicare benefit and is accessible for most Americans, access to palliative care is more limited.
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Law Enforcement Requests Conflict With Nurses’ Ethical Obligations
Nurses around the country are noticing a disturbing trend: Some patients suspected of violent crimes are admitted for medical care but are not arrested.
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Complex Research Ethics Question? Consultants Offer Their Expertise
The research ethics consultation works independently from the IRBs, although the IRBs occasionally reach out for help with challenging cases. Researchers typically seek help early in the process when thinking about recruitment or what populations to include.