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How Can IRBs Best Handle Ethical Conflicts in Social Media Research?
IRBs often review protocols in which investigators are using social media as a recruitment tool or a way to inform study participants about a particular disease. They might also use social media to keep tabs on potential or current research subjects. All of these intersections in the use of social media and human research protection can raise ethical red flags.
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How IRBs Can Fill in the RAC Gap
With changes to how gene therapy research is reviewed and regulated, IRBs will need to do more on their own to ensure study participant safety.
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The RAC Is Disappearing — What Will IRBs Be Missing?
The NIH has published new guidelines to streamline gene transfer research by eliminating RAC’s pre-review role and closing a national database of gene transfer studies.
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Workplace Violence, Bullying Associated With Cardiovascular Disease Risk
In a 12-year follow-up of surveyed Scandinavian employees, reported workplace violence and bullying increased the risk of future cardiovascular disease of a magnitude similar to other recognized cardiovascular disease risk factors.
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Are Calcium Channel Blockers Needed for Radial Artery Grafts?
A combined analysis of six trials comparing radial artery grafts vs. saphenous vein grafts for coronary bypass surgery revealed that patients taking calcium channel blockers for at least one year experienced fewer major cardiac events and fewer radial graft occlusions than those not so treated.
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Mildly Elevated Pulmonary Arterial Pressure Associated With Higher Mortality Rate
In a large cohort of patients referred for echocardiography, an estimated right ventricular systolic pressure > 30 mmHg was associated with higher mortality rates.
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Is Earlier Better With Oral P2Y12 Inhibition in STEMI Patients?
In a large retrospective analysis of patients in Sweden treated with primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction, a propensity-matched group of patients who received oral P2Y12 inhibitors at initial medical contact did not show improved outcomes vs. those receiving these agents at the time of PCI.
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Early vs. Delayed Cardioversion: A Nonshocking Result
For patients presenting to an ED with recent-onset atrial fibrillation, using rate control and outpatient cardioversion only as needed was associated with a high rate of spontaneous conversion within 48 hours of arrhythmia onset and noninferior short-term outcomes compared to immediate cardioversion in the ED.
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