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Clostridioides difficile and Reduced Vancomycin Susceptibility
Growth inhibition of Clostridioides difficile isolates from patients in Houston and Nairobi is requiring increasing concentrations of vancomycin, raising concerns about therapeutic efficacy.
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Omicron: Get Your Booster Dose!
While vaccination provides protection against the omicron variant of SARS-CoV-2, high-level protection from a need for hospitalization requires receipt of a booster dose.
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Was the 1889-1891 Russian Flu Really Coronavirus?
The 1889-1891 Russian flu pandemic was noted to spread rapidly through Western Europe, Great Britain, and North America. Contemporary clinical reports described prominent gastrointestinal, rheumatologic, and neurologic abnormalities (including loss of taste and smell), and pathologic reports described prominent thrombosis. A molecular clock analysis suggests a beta coronavirus emerged in humans following cross-species transmission around this time.
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Is a Cure for HIV Possible Without Stem Cell Transplantation?
In a 30-year-old woman with HIV not on antiretroviral therapy (the “Esperanza patient”), an analysis of 1.188 billion peripheral blood mononuclear cells and 503 million mononuclear cells from placental tissue revealed no genome-intact or replication-competent HIV-1 proviruses. This indicates a sterilizing cure of HIV-1 infection.
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Initial Antibiotic Choice for Neonatal Sepsis in Low- and Middle-Income Countries
Gram-negative rods are responsible for most neonatal sepsis in low- and middle-income countries. Ampicillin-gentamicin usually has been recommended for presumptive treatment, pending bacteriology results (when such tests are available). The results of a multinational study in Africa and Asia suggest resistance to standard therapy is widespread and that ceftazidime-amikacin might be a better option.
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Recognizing Stroke Mimics
The primary objective in this article is to review common stroke mimic etiologies, as well as discuss the key historical and physical examination characteristics associated with stroke mimics, and to present a diagnostic framework for approaching such cases.
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HHS Guidance Addresses HIPAA and Emergency Protective Orders
HHS recently issued guidance about HIPAA compliance when information must be released in conjunction with an extreme risk protection order. The guidance will be useful for risk managers and compliance officers, but may present some challenges when trying to adhere to HIPAA restrictions. -
HIPAA Safe Harbor Offers Limited But Important Protection
The HR 7898 HIPAA Safe Harbor Law, enacted in 2021, created a “safe harbor” for HIPAA-covered entities and their business associates when potentially facing fines and other penalties under HIPAA. But there are nuances to the law that risk managers and compliance officers must consider. -
Appeals Court Denies Hospital’s Objection to Expert Witness Report
This case shows the importance of expert testimony in reporting the standard of care. However, the legal requirements for expert witnesses are fairly minimal. -
Appellate Court Revives Lawsuit Against Hospital for Harvesting Organs Despite Objections
This case shows the standard of review for a plaintiff’s success on a claim of intentional infliction of emotional distress against a hospital.