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  • Patients with Diabetes Might Need Help Using Mobile Apps for Self-Care

    New research suggests older patients with diabetes and depression are less likely to use a smartphone app to help with diabetes self-management. Self-care apps are an important tool, and use likely will increase as people become more comfortable using them.

  • Post-Acute Care Transitions Were Problematic in Pandemic-Ravaged Areas

    The continuum of care hit roadblocks in some U.S. cities as the COVID-19 pandemic made post-acute care transitions extremely challenging. In New York City, the epicenter of the pandemic in March and April 2020, case managers needed to transition patients from acute care beds quickly, but had to adjust to surge obstacles to their usual post-acute options, according to the results of a recent study.

  • Military Service Can Be a Social Determinant of Health

    It may help case managers identify obstacles and problems for patients who are serving or have served in the military if they view this service as a social determinant of health, a researcher suggests. Veterans struggle with many of the same social determinants of health as non-veterans, including housing instability, gambling, substance use, depression, food insecurity, and post-traumatic stress disorder.

  • Acute Myocardial Infarction, or Related to COVID-19?

    The ECG in the figure was obtained from a man in his 30s. How would one interpret this tracing if told the patient’s only symptom was recent shortness of breath on exertion that he had not experienced?

  • Stem Cell Transplantation for MS Treatment

    In this small study of the effect of mesenchymal stem cell treatment, both intravenous and intrathecal, in patients with progressive multiple sclerosis, the treatment was shown to be safe, and there was a trend showing some benefit in slowing disease progression, compared to the sham group. A larger randomized controlled trial is needed to confirm these early findings.

  • Spontaneous Intracranial Hypotension Syndrome

    A systematic review of spontaneous intracranial hypotension demonstrates heterogeneity in clinical and radiographic presentations. Diagnostic studies, such as brain imaging and lumbar puncture, may be unrevealing, and the clinician may have to rely on symptom patterns alone to make a diagnosis.

  • Efficacy and Safety of Cannabidiol in Treatment of Focal Seizures Associated with Tuberous Sclerosis Complex

    Cannabidiol used as an add-on therapy for intractable focal seizures in patients with tuberous sclerosis complex was efficacious. Cannabidiol also had an acceptable adverse event profile, but frequently induced transient elevation of liver enzymes.

  • Gluten/Celiac Disease Neuropathy

    Gluten neuropathy should be suspected in any patient who presents with a neuropathy and has a history of gastrointestinal disease. The diagnosis is made using blood serology plus intestinal mucosal biopsy.

  • Long-Term Treatment of Hereditary Amyloid Neuropathy with Patisiran

    Hereditary transthyretin-mediated amyloidosis with polyneuropathy is effectively treated by patisiran, a lipid nanoparticle ribonucleic acid interference that binds to transthyretin (TTR) messenger RNA and inhibits TTR production in the liver, resulting in reduction of the serum TTR concentration. Treatment effect has been sustained during a five-year open-label extension study.

  • Orthopedic Excitement in 2021

    It is critical to secure commitment from surgeons before investing time and money in preparing facilities for newly approved procedures. Surgeons can provide valuable input on equipment needs. Be aggressive, but be smart.