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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.
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Ketogenic Diet Improves Cognition, Daily Function in Alzheimer’s Disease Patients
In a randomized, crossover trial, patients with Alzheimer’s disease on a ketogenic diet for 12 weeks demonstrated improved cognition, daily function, and quality of life.
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Pitfalls in the Diagnosis of CIDP
Chronic inflammatory demyelinating polyradiculoneuropathy is commonly misdiagnosed. It is important to adhere to established diagnostic criteria and to regularly re-evaluate all patients given this diagnosis.
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Special Report from the 2021 International Stroke Conference
These reviews of studies presented at the virtual 2021 International Stroke Conference were written by Neurology Alert's editor. All comments and opinions are solely those of the editor.
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Transdiagnostic Cognitive Behavioral Therapy in Young Patients
This Danish randomized clinical trial compares a new form of cognitive behavioral therapy delivered in a community setting to “treatment as usual” for children and teens with emotional problems and shows advantages in multiple arenas, including parent-reported changes in child distress and impairment.
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Air Filters and Asthma
Asthmatic children showed improved small airway mechanics following indoor filtration of particulates (2.5 µm and greater) using high-efficiency particulate air filtration devices.
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Loneliness and Type 2 Diabetes Incidence
Loneliness appears to be an independent risk factor for type 2 diabetes, although further research to identify the causal relationship between loneliness and type 2 diabetes development is needed.
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Virtual Site Training Expands During the Pandemic
Virtual training for clinical trial teams may have existed for years, but it has gained significant attention during the COVID-19 pandemic. Experts expect the popularity of this kind of training to increase, even after COVID-19 restrictions are relaxed. -
Exploitation Issues Arise in Study of Human Subject Incentive Payments
As IRBs review participant incentives for studies, they assess whether the incentives are coercive or exploitive. New research provides a snapshot of the diversity of these incentive offerings, revealing monetary payments for biomedical studies tend to be 10 times higher than payments for sociobehavioral studies. -
Reliance Teams Strengthen Relationships with Central IRB
IRBs and research institutions continue to hammer out processes and best practices related to the revised Common Rule. As one IRB found, this process requires a team effort. When collaborative IRB requests began to increase, the Augusta (GA) University IRB office formed a reliance team. The IRB also designated one team member, a reliance coordinator, to handle issues related to reliance agreements. A recent study revealed the reliance team helps IRB offices with collaboration and reviewing reliance agreements to ensure the research is in accordance with local policies. The team also can help investigators navigate through reliance process.