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Pediatric Malaria
Malaria is present in all continents except Antarctica and has led to significant human illness and death. Children account for the majority of malaria deaths globally, making malaria a significant contributor to childhood mortality worldwide. Malaria is a mandatory consideration for children with fever who are returned travelers, since the disease process can lead to significant mortality and rapid clinical decline. The authors provide an update and current state of care for malaria in the pediatric population. -
Finerenone Tablets (Kerendia)
Finerenone can be prescribed to lower the risk of sustained estimated glomerular filtration rate decline, cardiovascular death, non-fatal myocardial infarction, end-stage kidney disease, and hospitalization from heart failure in adults with chronic kidney disease associated with type 2 diabetes. -
Association of Sleepwalking and REM Sleep Behavior Disorder in Men with Parkinson’s
In this retrospective, cross-sectional study of men, both sleepwalking and rapid eye movement sleep behavior disorder were associated with the development of Parkinson’s disease. -
OB/GYN Clinical Alert Welcomes Maria F. Gallo, PhD
Maria F. Gallo, PhD, joins OB/GYN Clinical Alert. -
Anticholinergic Use for Three Months or More Increases Dementia Risk
There is a significant increase in dementia risk associated with the use of anticholinergic medications for three months or longer. -
LMWH vs. UFH in Pregnant Women Undergoing Anticoagulation
In this retrospective cohort study of pregnant women treated with low-molecular-weight heparin (LMWH) alone compared to those switched to unfractionated heparin (UFH) in the peripartum period, the outcomes were similar in both groups.
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Evaluation and Treatment of Women with Symptoms of Recurrent UTIs
Only 33% of women presenting to a urogynecology practice with symptoms of recurrent urinary tract infections met diagnostic criteria for recurrent urinary tract infections. The use of preventive strategies can be improved.
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Ketamine Use in the Prevention of Postpartum Depression Is Premature
A double-blinded, randomized clinical trial of 134 low-risk pregnant women in Iran undergoing scheduled cesarean deliveries was conducted to address if a single dose of ketamine during anesthesia induction has a role in the prevention of postpartum depression. The authors reported that depression scores using the Edinburgh Postnatal Depression Scale at two and four weeks after the cesarean delivery were significantly lower in the ketamine group vs. the control group.
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Is Black Race Associated with Major Depression Following Early Pregnancy Loss?
Reporting symptoms of having major depression one month after treatment for early pregnancy loss was about twice as common among Black women compared to non-Black women.
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Results of HIV Vaginal Ring Study Demonstrate Adherence
Adherence to the dapivirine vaginal ring, a topical HIV-1 agent to prevent HIV infection, improved over time, according to the results of a recent study. The vaginal ring is an investigational pre-exposure prophylactic agent that is inserted in the vagina. The silicone matrix ring is loaded with a microbicidal agent.