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Critical Care Alert – August 1, 2019
August 1, 2019
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Heparin-Induced Thrombocytopenia: What’s the Latest?
Heparin-induced thrombocytopenia is an iatrogenic, potentially life-threatening complication that occurs after exposure to heparin therapy in hospitalized patients. Early recognition and timely initiation of treatment are critical for improved prognosis.
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Impact of Early Low-Dose Norepinephrine in Adults Experiencing Sepsis With Hypotension
Adult patients experiencing sepsis with hypotension but who did not meet the definition of septic shock received a median of 800 mL of intravenous fluid prior to initiation of norepinephrine 0.05 mcg/kg/min as a non-titratable infusion. Patients in this early vasopressor group had much lower odds of failing to achieve their primary outcome of adequate mean arterial pressure and tissue perfusion when early norepinephrine was provided.
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Trajectory of Physical Function Recovery May Help Inform Prognosis for Survivors of Acute Respiratory Failure
There are several distinct trajectories of recovery after acute respiratory failure. The group with the highest physical function consisted primarily of younger women who experienced less continuous sedation time and shorter ICU length of stay.
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