A study of the echocardiographic characteristics of symptomatic patients with obstructive hypertrophic cardiomyopathy treated with mavacamten showed a persistent 30-week improvement in several key pathophysiologic characteristics.
In this randomized trial of post-transcatheter aortic valve replacement patients with atrial fibrillation, edoxaban was noninferior to vitamin K antagonists with regard to a composite of adverse endpoints, but was associated with a higher rate of major bleeding.
A study of asymptomatic subjects without known cardiovascular disease undergoing treadmill exercise testing and followed for a mean of 20 years showed high-grade premature ventricular contractions during exercise recovery (but not during exercise) are predictive of subsequent cardiovascular mortality.
Using a handheld point-of-care ultrasound device to estimate right atrial pressure from images of the jugular vein resulted in a higher imaging success rate vs. visual inspection and a reasonably accurate estimation, especially in those with elevated right atrial pressures.
Using cardiac MRI as a gold standard, the presence of a flail mitral leaflet or a wall-impinging mitral regurgitant jet on transthoracic echocardiography were associated with severe mitral regurgitation, but not diagnostic of it.
