Clinical Cardiology Alert – September 1, 2021

September 1, 2021

• Alcohol Consumption and Atrial Fibrillation

  An analysis of the UK Biobank database revealed low levels of alcohol consumption, especially with wine and spirits, is associated with the lowest incidence of atrial fibrillation.

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• Coffee Consumption and Tachyarrhythmias

  An analysis demonstrated an inverse association of coffee consumption and cardiac arrhythmias, which was not altered by genetic variations in caffeine metabolism, age, or sex.

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• The Difficulty of Showing Benefit of Cerebral Protection Devices During TAVR

  In this trial of cerebral protection in transcatheter aortic valve replacement, the TriGUARD device was safe vs. historical controls, but failed to meet its primary efficacy endpoint.

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• Early Physical Rehabilitation in Acutely Hospitalized Heart Failure Patients

  A tailored, progressive physical rehabilitation program started in the hospital and continued for three months in older, relatively frail acute heart failure admissions resulted in significantly improved physical function vs. usual care but did not reduce six-month readmission rates.

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• Value of Optimal Medical Therapy After Revascularization

  Patients with three-vessel or left main coronary artery disease randomized to coronary bypass surgery vs. percutaneous therapy on optimal medical therapy at five years with three or four of the recommended drugs recorded a lower 10-year all-cause mortality rate vs. those on ≤ 2 drugs.

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