Clinical Cardiology Alert – December 1, 2017
December 1, 2017
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ORBITA: Learning the Right Lessons From a Sham-controlled Trial of Angioplasty
In this sham-controlled trial of 200 patients with single-vessel coronary artery disease and stable angina, percutaneous coronary intervention did not increase exercise time significantly compared to a placebo procedure.
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Risk of Major Bleeding With Concurrent Medications in Atrial Fibrillation Patients Taking New Oral Anticoagulants
A large nationwide comprehensive clinical database showed that concomitant use of the new oral anticoagulants with amiodarone, fluconazole, rifampin, and phenytoin increases the risk of major bleeding.
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Value of Liver Function Tests in Cardiogenic Shock
A prospective, multicentered, observational study of patients admitted with cardiogenic shock showed that a > 20% rise in alanine aminotransferase in the first 24 hours is associated highly and independently with 90-day mortality.
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Cardiac Magnetic Resonance Identifies High-risk Patients With Acute Myocarditis and Preserved Ejection Fraction
In patients with acute myocarditis and preserved left ventricular ejection fraction who underwent cardiac magnetic resonance, the presence of late gadolinium enhancement involving the midwall layer of the anteroseptum was associated with a worse prognosis.
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Optimizing Outcomes for Invasive Treatment of Long-standing, Persistent Atrial Fibrillation
In patients with long-standing, persistent atrial fibrillation, outcomes with an electrophysiologically guided thoracoscopic surgical ablation procedure were superior to a standard catheter approach.