Clinical Cardiology Alert – October 1, 2015
October 1, 2015
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A Revolution in Pacing?
Leadless pacemakers appeared to be effective and relatively safe in short-term follow-up.
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MATRIX Reloaded: Bivalirudin Fails to Best Heparin in ACS
Among patients with acute coronary syndromes referred for percutaneous intervention, bivalirudin did not lower rates of major adverse cardiovascular events or net adverse clinical outcomes as compared with unfractionated heparin.
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Echocardiographic Parameters Predict Outcome in Peripartum Cardiomyopathy
Poor baseline left ventricular ejection fraction, greater degree of left ventricular dilation, and black race predict poorer subsequent recovery with conventional therapy.
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Role of Transthoracic Echo in Staph Bacteremia
In patients without community-acquired Staph bacteremia, a high-risk cardiac condition, or IV drug use, a negative transthoracic echo excluded infective endocarditis.
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Two Drugs Better Than One for Pulmonary Arterial Hypertension
Among subjects with pulmonary arterial hypertension who are treatment naïve, initial combination therapy with tadalafil and ambrisentan is associated with significantly lower risk of clinical failure than initial monotherapy with either tadalafil or ambrisentan.