Clinical Cardiology Alert – December 1, 2007
December 1, 2007
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Ranolazine for ACS
This report from the merlin-timi 36 investigators describes the effects of ranolazine on spontaneous arrhythmias in patients with acute coronary syndrome (ACS). -
Cognitive Decline After CABG
Cognitive decline after surgery requiring cardio-pulmonary bypass (CPB) may be due to cellular debris picked up by the cardiotomy suction device. -
Minimal Extracorporeal Circulation vs Off-Pump CABG
Off-pump CABG avoids the complications of cardiopulmonary bypass (CPB), but is technically demanding. -
Weight Gain: Predictor of Heart Failure Hospitalization
Weight gain has long been used as a marker of fluid retention in heart failure patients. It is a cheap, simple test that can be performed daily in patients' homes. -
Sildenafil and Exercise Capacity in Heart Failure
An interesting therapeutic concept that has been put into clinical practice in the past several years is the use of nitric oxide donors for pulmonary hypertension. -
Statin Therapy with Major Vascular Surgery
Cardiac death and perioperative myocardial infarctions occur in 2-20% (mean 6) of major noncardiac vascular surgery. Statins have been shown to have a protective effect, but the exact mechanism of this benefit is unclear. -
Sex Differences in ICD Use
Lesley and colleagues analyzed a 5% national sample of Medicare inpatient, outpatient, and carrier files to examine the use of ICD therapy for both primary and secondary prevention of sudden cardiac death. -
Pharmacology Watch
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Clinical Briefs in Primary Care Supplement