Clinical Cardiology Alert – October 1, 2005
October 1, 2005
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Clinical Briefs in Primary Care supplement
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Pharmacology Watch
The Use of Prophylactic Antibiotics for Neutropenia; Is It Hot In Here?; Homeopathy vs Conventional Medicine; FDA Actions -
Interventional vs Conservative Strategy for Non-ST Elevation Acute Coronary Syndrome
More recent trials, and meta-analyses of all trials, have shown a reduction in death and myocardial infarction (MI) with a routine invasive strategy vs an ischemia or symptom-driven invasive strategy over 6-24 months for patients with non-ST elevation (E) acute coronary syndrome (ACS). However, an increase in death during the initial hospitalization in the routine invasive arm makes long-term outcome data important. Thus, the British Heart Foundation RITA 3 trial 5-year data are of interest. -
Dual Therapy for Acute STEMI: Has The Time Arrived?
In patients presenting with high-risk STEMI, TNK plus immediate angioplasty reduced the risk of recurrent ischemic events compared with TNK alone and was not associated with an increase in major bleeding complications. -
Reversal of Cardiomyopathy in Patients With Repetitive Ventricular Ectopy
Arrhythmia is the primary problem rather than a marker of an underlying cardiomyopathy. -
Left Atrial Size in Competitive Athletes
Left atrial remodeling in competitive athletes may be regarded as a physiologic adaptation to exercise conditioning, largely without adverse clinical consequences. -
QRS Duration Does Not Predict Occurrence of VT in Patients with ICDs
QRS duration does not predict occurrence of VT or VF necessitating ICD therapy. -
Risk of Noncardiac Surgery with Aortic Stenosis
Aortic stenosis increases the risk of MI, but not overall mortality with noncardiac surgery.