OB/GYN Clinical Alert – November 1, 2021

November 1, 2021

• SARS-CoV-2 Infection During Pregnancy and Increased Risk of Preeclampsia

  A meta-analysis of 28 observational studies found that having SARS-CoV-2 infection during pregnancy was associated with a 58% increase in the adjusted odds of having preeclampsia compared to those without SARS-CoV-2 infection during pregnancy.

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• Do Women 64 to 66 Years of Age Qualify to Discontinue Cervical Screening?

  These studies evaluated adherence to national guidelines for exiting from cervical cancer screening at 65 years of age and managing abnormal results on screening with human papillomavirus (HPV) and Pap co-testing and found that the majority of women 64 to 66 years of age do not qualify to discontinue screening, and the majority of women with discordant Pap and HPV test results are managed incorrectly.

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• Menopausal Hot Flashes: Can a Plant-Based Diet Provide Effective Treatment?

  In this clinical trial, women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% compared to 49% in the control group over 12 weeks of observation.

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• Use of Ursodeoxycholic Acid in Pregnant Women with Obstetric Cholestasis

  Ursodeoxycholic acid might be beneficial in reducing the risk of spontaneous preterm birth and meconium-stained amniotic fluid, but not stillbirths, in women with pregnancies complicated by obstetric cholestasis.

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