OB/GYN Clinical Alert – August 1, 2020
August 1, 2020
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Is Nitrous Oxide an Effective Analgesic During Labor?
In this prospective cohort study at one large academic medical center in Colorado, 31% of women who opted for nitrous oxide for analgesia during labor did not require any other source of analgesia, such as an epidural or intravenous opioids. Risk factors for conversion to other modalities included labor induction, oxytocin augmentation, and labor after cesarean.
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Macrolides During Pregnancy — Behind the Headlines
Despite published concerns, there is no good evidence that macrolide use during pregnancy causes birth defects.
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Many Serious Cardiac Complications of Pregnancy Are Preventable
Investigators determined about half of serious cardiac complications of pregnancy are preventable.
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.
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