OB/GYN Clinical Alert – June 1, 2019

June 1, 2019

• Multimodal Stepwise Post-Cesarean Pain Control Reduces Opioid Use

  These investigators found that the routine use of acetaminophen alone rather than a combination acetaminophen-opioid significantly reduced overall and daily opioid use. In addition, there was no worse effect on overall pain score or length of stay.

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• Does Hormone Therapy Increase the Risk of Alzheimer’s Disease?

  A large Finnish case-control study suggests that postmenopausal hormone therapy results in a 9-17% increase in the risk of Alzheimer’s disease. However, the small effect size, and likely confounding of use effect, does not provide strong evidence for a causal relationship.

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• Perioperative Antibiotics in Gynecologic Surgery: The Case for Myomectomy

  The authors of a retrospective cohort study suggest that perioperative antibiotics reduce the risk of surgical site infection in women undergoing myomectomy.

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• Estrogens Used in Hormonal Therapy

  To practice as a consultant in reproductive medicine, clinicians require a strong background in hormonal therapy. In this feature, we will review the role of steroidal estrogens used in contraceptive and hormone therapy.

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