OB/GYN Clinical Alert (Vol. 33, No. 2) – June 2016

June 1, 2016

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Early Initiation of Postmenopausal Estrogen Therapy
Women randomized to oral estradiol therapy showed less progression of subclinical atherosclerosis than those who received placebo.
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Pessaries in Patients with Short Cervices
The largest multicenter, randomized, controlled trial so far has found no significant benefit of pessaries to prevent preterm birth or to decrease neonatal morbidity in patients with short cervices.
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Colpocleisis: Body Image, Satisfaction, and Regret at 24 Week
Colpocleisis is an effective surgical treatment for pelvic organ prolapse. Women report high satisfaction and low regret.
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Vulvar Squamous Intraepithelial Lesions
The International Society for the Study of Vulvovaginal Disease adapted Lower Anogenital Squamous Terminology to the specifics of the vulva and released the 2015 terminology. Vulvar Low-grade squamous intraepithelial lesion is benign and includes HPV effect and flat condyloma. Vulvarhigh-grade squamous intraepithelial lesion is the usual HPV-associated type of high-grade vulvar intraepithelial neoplasia and the non-HPV-associated type is labeled differentiated-type vulvar intraepithelial neoplasia.
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In Memoriam
On May 4, 2016, Dan Mishell, MD, passed away at home surrounded by family.
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