OB/GYN Clinical Alert – April 1, 2015
April 1, 2015
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Finding New Clinical Activity in Endometrial Cancer from Optimizing Molecular Pathways
Everolimus, combined with letrozole, produced unexpected clinical activity in a cohort of previously treated recurrent endometrial cancer patients.
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Hormonal Contraception and Glioma: Is There Reason for Concern?
A large case-control study using the Danish National database found a slight increase in the risk of glioma in ever-users of hormonal contraception, which increased with duration of use. Users of progestin-only methods were at higher risk. However, these findings should not influence clinical practice or perception of contraceptive safety.
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NIPT and Invasive Procedures
A single prenatal testing center with a large volume of patients has experienced a dramatic drop in the rate of chorionic villus sampling and amniocentesis after the introduction of noninvasive prenatal testing.
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Postoperative Delirium in Older Adults
The elderly operative patient has very different and specific needs compared to a younger woman. In addition to a higher risk of medical comorbidities, elderly women are affected by cognitive impairment, depression, gait, and balance disturbances.
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Farewell and Welcome
Dr. Robert Coleman, a member of the editorial board of OB/GYN Clinical Alert since 2004, has been elected as the next President of the Society of Gynecologic Oncologists.