OB/GYN Clinical Alert – December 1, 2007
December 1, 2007
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Long-term Results with Tamoxifen in Prevention of Breast Cancer
The Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial began in 1986, enrolling 2,471 women with a positive first-degree family history of breast cancer.1 The treatment group received 20 mg tamoxifen daily for 8 years. -
Intravenous Bisphosphonate and Facial Bones
Wilkinson and colleagues from the University of Texas in Galveston analyzed information from the Surveillance, Epidemiology, and End Results (SEER) databank linked to Medicare claims. -
Manual Rotation in Occiput Posterior or Transverse Positions — Risk Factors and Consequences on the Cesarean Delivery Rate
The author reviewed a year's worth of data from a busy hospital in France where manual rotation was liberally used. The procedure, which will be described below, was used in 796 patients, in whom 85 (9.7%) failed. -
Surgical Management of Primary Dysmenorrhea: Anything New?
In a study of 82 patients with primary dysmenorrhea who had been randomized to undergoing either LUNA or LUNA + PN, the two groups had comparable results (69% improved in the LUNA group; 73% in the LUNA+PN group) at up to 12 months of follow-up. -
SGO's Statement on Risk Assessment for Inherited Gynecologic Cancer Predisposition
Germline mutations in BRCA1 or BRCA2 associated with the Hereditary Breast/Ovarian Cancer syndrome have an increased lifetime risk for breast (up to 85%) and ovarian (up to 46% BRCA1, up to 27% BRCA2) cancer. -
Oral Contraceptives and Breast Cancer in Young Women
A team of epidemiologists from several institutions in the US performed a case-control study of the association between oral contraceptive use and lobular and ductal breast cancer occurring in young women (under age 44). -
Pharmacology Watch: Adult Immunization Guidelines from CDC Released
In this issue: Updated Immunization Guidelines from the CDC; Do antivirals have a role in the treatment of Bell's palsy? Topiramate is a promising treatment for alcohol dependence; and FDA Actions. -
Clinical Briefs in Primary Care supplement