OB/GYN Clinical Alert – November 1, 2007
November 1, 2007
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Prophylactic Antibiotics and Cesarean Section
The title says it all in this randomized controlled trial by Sullivan and colleagues "Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing post-cesarean infectious morbidity." -
Results from the Cancelled WISDOM Trial
WISDOM was a multicenter, randomized, placebo-controlled clinical trial of postmenopausal hormone therapy that began recruitment in 1999 in the U.K. and in 2000 in Australia and New Zealand. The trial was prematurely cancelled in 2002 after the initial publication of results in the Women's Health Initiative (WHI). -
Complications of Exteriorization Compared with In Situ Uterine Repair at Cesarean Delivery under Spinal Anesthesia
It is still common practice to exteriorize the uterus during repair of the uterine incision during cesarean section. The rationale to support this maneuver is that it makes the job easier, faster, and it decreases blood loss. -
Can Clinical Empathy be Taught?
It is one thing to be empathetic, but it is something quite different to be able to convey empathy to the patient. -
Do Different OCP's Cause Different Problems?
Between 2000 and 2004 these French investigators studied 2863 women to determine the frequency of reported symptoms (weight gain, nausea, breast tenderness, swollen legs, fewer periods, breakthrough bleeding, painful/heavy periods) relative to the type of OCP taken (estrogen dose, progestin component, sequence of administration). -
Pharmacology Watch: Are Thiazolidinediones (TZDs) Safe?
Zometa and hip fractures; Merck HIV Vaccine Ineffective in Clinical Trial; Thimerosal and Mercury Exposure; FDA Actions -
Clinical Briefs in Primary Care supplement