OB/GYN Clinical Alert – January 1, 2007

January 1, 2007

• Oral Contraceptives and Pre-Menopausal Breast Cancer

  Kahlenborn and colleagues performed a meta-analysis of case-control studies published after 1979 that focused on the use of oral contraceptives and the risk of premenopausal breast cancer.

  Read more

• Outcome of Cytoreductive Surgery in Primary Ovarian Cancer: What is "Optimal"?

  The resection of tumor nodules (or cytoreduction) before primary chemotherapy has been linked closely with survival in patients with advanced epithelial ovarian cancer. Chi and colleagues set out to evaluate the merits of cytoreduction completeness in a homogeneous cohort of ovarian cancer patients with bulky metastatic disease.

  Read more

• Pregnancy Loss Rates After Midtrimester Amniocentesis

  The lead paper in the November issue of Obstetrics and Gynecology should stimulate lively discussion regarding the counseling of patients of advanced maternal age (AMA), and, if taken at face value, could impact the field of prenatal diagnosis, in general.

  Read more

• Post-Menopausal Hormone Therapy and Ovarian Cancer Risk

  Lacey and colleagues from the National Cancer Institute reported the results of postmenopausal hormone exposure in a cohort study with 214 cases of ovarian cancer.1 The over-all cohort of 97,368 women constituted the NIH-AARP Diet and Health Study.

  Read more

• Pharmacology Watch: Study: Long-Term Use of Clopidogrel for DES Patients

  Drug Labels A Prescription for Misunderstanding?; Osteonecrosis of the Jaw New Side-Effect to Bisphosphate Use; Beta-Blockers and Depression Unlinked?; FDA Actions

  Read more

• Clinical Briefs in Primary Care supplement

  Read more