OB/GYN Clinical Alert – September 1, 2006
September 1, 2006
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Estrogen, Testosterone, and Breast Cancer in the Nurses' Health Study
The nurses' health study reported the risk of invasive breast cancer associated with the use of combined estrogen and testosterone. At the beginning of this cohort study, only 33 women reported testosterone use, but over the next 10 years this number increased to 550. -
OB/GYNs' Attitudes Toward Hysterectomy
A survey was mailed to 500 members of the American College of Obstetricians and Gynecologists presenting a case of symptomatic fibroids. The respondents were asked to choose hysterectomy or a uterus-sparing procedure, 49% responded. -
New Light on the Link Between Chronic Stress and Ovarian Cancer Tumorigenesis
While stress has well documented effects on immune, neurochemical and endocrinological function, its role in cancer progression is less well understood. It is appreciated, in preclinical studies, that stress can affect the growth of some tumors through modulation of the immune response to tumor cells. -
Managing Poor Response to Hormone Therapy
Hormone therapy is highly effective for relieving symptoms associated with menopause and for preventing postmenopausal osteoporosis. Some women, however, respond unsatisfactorily to standard doses of hormone therapy. -
The Peritoneum — To Close or Not to Close During a Cesarean Section?
There continues to be controversy regarding the merits and risks of one- or two-layer closure of the uterus during cesarean section. Also, although opinions abound concerning whether or not to close the peritoneum during a cesarean section, until now there has been sparse evidence in the literature to back either side. -
Breast Cancer Risk in the WHI Estrogen-Progestin Trial Arm
Anderson and colleagues from the WHI performed subgroup analyses focusing on how prior hormone therapy use influenced the risk of breast cancer found in the estrogen-progestin trial arm. -
Pharmacology Watch: Raloxifene's Role for Estrogen- and Age-Related Problems
The Truth About Multivitamins; Statins and Hepatitis C; Preventing Hot Flashes; FDA News -
Clinical Briefs in Primary Care supplement