OB/GYN Clinical Alert – April 1, 2012
April 1, 2012
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Ulipristal Acetate for Uterine Fibroids
The results of the PEARL I and PEARL II studies were published recently in the same issue of the New England Journal of Medicine. Both were well-designed, randomized, controlled, double-blinded studies that assessed the safety and efficacy of ulipristal acetate (UPA) for the treatment of symptomatic uterine fibroids. -
Platelets and Cancer: Friend or Foe?
It has been long recognized that thrombocytosis (defined as a platelet count > 450,000/mm3) frequently accompanies the diagnosis of advanced cancer and has been associated with poor outcomes. -
Operative Delivery
Managing labor is an art, while the actual delivery process requires the addition of skill and experience. Yet, the decision of which route of delivery to employ may have the greatest impact on outcome. A recent article deals with neonatal morbidity, including an important contributor, intracranial injury, and its association with various forms of operative delivery. -
Postoperative LNG-IUS for Chronic Pelvic Pain
The authors conducted a double-blind, randomized, controlled trial to determine whether the postoperative use of a levonorgestrel intrauterine system (LNG-IUS) was an effective treatment for chronic pelvic pain in women with endometriosis. -
Special Feature: How Often Should Healthy Women Be Screened for Osteoporosis?
In this study, 4957 women aged 67 and older were followed prospectively for up to 15 years. Statistical models were used to calculate the bone mineral density (BMD) testing interval for women with normal BMD and those with mild, moderate, or advanced osteopenia. -
Pharmacology Watch: Statins and the Risk of Diabetes
In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions. -
Clinical Briefs in Primary Care supplement