OB/GYN Clinical Alert – February 1, 2012

February 1, 2012

• Do Combined Oral Contraceptives Worsen Breastfeeding Outcomes?

  The authors performed a randomized, double-blind study to compare the effects of progestin-only and combined hormonal contraceptive pills on rates of breastfeeding continuation in postpartum women.

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• Is There an Increased Risk of HIV Transmission with Use of Hormonal Contraception?

  Heffron et al conducted a secondary analysis of two longitudinal studies (2004-2010) performed in Africa.

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• Hyperemesis Gravidarum and Adverse Perinatal Outcomes

  How often are we asked whether a patient who has had severe nausea and vomiting in early pregnancy has a greater chance of adverse outcome in her pregnancy?

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• Do We Have a New Standard of Care for Advanced Ovarian Cancer?

  Vascular endothelial growth factor (vegf) is a key factor in the normal and tumor microenvironment regulating angiogenesis.

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• Pharmacology Watch: New, Shorter Treatment Regimen for Tuberculosis

  In this issue: New treatment for TB; safety of dabigatran; quality of antidepressants; systolic hypertension treatment; and FDA actions.

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• Clinical Briefs in Primary Care supplement

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