OB/GYN Clinical Alert – June 1, 2009

June 1, 2009

• Thrombophilia and Pre-eclampsia

  One of the most confusing areas in medicine, which spills over into obstetrics, is thrombophilia, and seemingly every year a new antibody affecting the clotting system emerges that causes worry. One of the worries involves a possible link with pre-eclampsia.

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• Fertility Following Oral Contraceptives

  A review of any publication from 1960 to 2007 with the main outcome of time to fertility following oral contraceptive discontinuation was performed.

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• Arzoxifene for Prevention of Osteoporosis

  Arzoxifene is being developed by Eli Lilly and Co. to prevent bone loss and treat osteoporosis.

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• Prognosis for Spontaneous Labor in Women with Uncomplicated Term Pregnancies

  During the last two months an unusual number of papers were published which, while not having earth-shaking scientific value, should have some clinical impact.

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• Special Feature: Swing and Miss?!? Efforts in Front-line Ovarian Cancer Chemotherapy Development

  Data from the Surveillance Epidemiology and End Results (SEER) registry have consistently demonstrated improved life expectancy for women with epithelial ovarian cancer every year since 1973.

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• Pharmacology Watch: Guidance on the Appropriate Use of NSAIDs

  n this issue: NSAIDs in the elderly; managing GI and CVD risk with NSAIDs; low-dose naltrexone and fibromyalgia; treating glucocorticoid-induced bone loss; FDA Actions.

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• Clinical Briefs in Primary Care supplement

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