OB/GYN Clinical Alert – March 1, 2010

March 1, 2010

• Betamimetics in Pregnancy Related to Autism: Really?

  In the last two months, there were four articles in the American Journal of Obstetrics & Gynecology and Obstetrics & Gynecology dealing with drugs that are commonly used in pregnancy and their possible contribution to adverse outcomes. One of these articles was particularly attention-getting.

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• Breast Tenderness, HRT, and Breast Cancer

  The authors analyzed data from the Women's Health Initiative (WHI) combined Estrogen/Progestin Trial to determine if new-onset breast tenderness (NOBT) was associated with the development of breast cancer.

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• Bethesda Guidelines for Lynch Syndrome Screening Appear to Improve the Amsterdam Criteria

  Lynch Syndrome (LS) is a familial colorectal cancer syndrome, which occurs as a result of autosomal dominant inheritance of DNA mismatch repair genes.

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• Special Feature: Robotic Surgery: Time to Do Some Soul-searching

  Data continue to be generated related to the use of robotic surgery in gynecology. At the current time, what the future holds for this latest technology within our specialty is anyone's guess.

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• Clinical Briefs in Primary Care supplement

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• Pharmacology Watch: Oral Treatments for Relapsing-remitting MS

  In this issue: Two oral medications for relapsing-remitting MS in phase III development; antihypertensives find new uses; Ginkgo biloba does not prevent cognitive decline in elderly; and FDA Actions.

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